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Vaccine hope for one in 400 people with genetic disorder that increases cancer risk
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10th September 2024 - The Independent
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Doctors are taking the first steps to develop a vaccine for people with a condition that increases their risk of a number of cancers.
Lynch syndrome is caused by a mutation in the gene that fixes mistakes in DNA when it is copied, which can lead to uncontrolled cell growth.
An estimated one in 400 people in England have the condition, according to the NHS, although only 5% are aware they are living with it. Last year, the health service started rolling out a genetic test for Lynch syndrome.
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People with the condition have a higher risk of developing cancers of the bowel, womb and ovaries.
About 1,100 bowel cancer cases in England each year are caused by Lynch syndrome and the condition is thought to increase the lifetime risk of the disease by 80%.
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